The KNG1 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to Kininogen 1, and KNG1. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The KNG1 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, and Western Blot.
Description
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene